반응 #4376
ord-06fbe5b3f1e34d95a302135ea4df5b48
반응 방정식
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1기타the solid collected
- 2기타It was recrystallized from toluene
실험 절차
A solution of 45 g (0.27 mole) of 3-methoxybenzeneacetic acid, 52.6 g (0.32 mole) of iodine monochloride and 1 g of iodine was allowed to stand in 500 ml of glacial acetic acid for six days at room temperature. The reaction was poured into water and the solid collected. It was recrystallized from toluene to give 51 g of crystalline 2-iodo-5-methoxybenzeneacetic acid, mp 133.5°-134.5° C. (65% yield).