반응 #43715

반응 방정식

2,3,5-trifluorobenzaldehyde

sodium hydride

methyl mercaptoacetate

→

title compound

Methyl5,7-difluoro-1-benzothiophene-2-carboxylate

반응 조건

실험 절차

Using 3.94 g (24.6 mmol) of 2,3,5-trifluorobenzaldehyde, 1.48 g (36.9 mmol) of sodium hydride (60% pure) and 2.88 g (27.1 mmol) of methyl mercaptoacetate, 3.58 g (56% of theory) of the title compound are obtained in a purity of 89%. Recrystallization from methanol gives the product in a purity of 97%.

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