반응 #4348

반응 방정식

3-methoxy-6-methylaniline

sulfamic acid

→

2-methoxy-5-methylsulfanilic acid

용매

Acetonitrile

반응 조건

후처리

1. 1
   온도the mixture was heated to temperature of from 150° to 160° C.
2. 2
   온도maintained
3. 3
   기타the crystals thus deposited were collected
4. 4
   workup.DISSOLUTIONThe crystals were dissolved in an aqueous solution of sodium hydroxide
5. 5
   여과the solution was filtered
6. 6
   여과the crystals thus deposited were collected by filtration

실험 절차

23.1 g of 3-methoxy-6-methylaniline and 16.4 g of sulfamic acid were put into a 100 ml egg-plant type flask and the mixture was heated to temperature of from 150° to 160° C. and maintained thereat for 2 hours. Acetonitrile was added to the reaction mixture and the crystals thus deposited were collected. The crystals were dissolved in an aqueous solution of sodium hydroxide, the solution was filtered and acidified with hydrochloric acid, and the crystals thus deposited were collected by filtration.

출처