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2-[(S)-2-fluoromethyl-1-pyrrolidinyl]ethanol

4-benzyloxy-1-(4-hydroxyphenyl)-1H-pyridin-2-one

4-(4-fluorobenzyloxy)-1-(4-hydroxyphenyl)-1H-pyridin-2-one

→

title compound

4-(4-fluorobenzyloxy)-1-(4-{2-[(2S)-2-fluoromethyl-1-pyrrolidinyl]ethoxy}phenyl)-1H-pyridin-2-one

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실험 절차

Step (3) of Example 12 was repeated except that 4-benzyloxy-1-(4-hydroxyphenyl)-1H-pyridin-2-one and 2-(1-pyrrolidine)ethanol were replaced with 4-(4-fluorobenzyloxy)-1-(4-hydroxyphenyl)-1H-pyridin-2-one (Step (2) of Example 28) and 2-[(S)-2-fluoromethyl-1-pyrrolidinyl]ethanol, respectively, to provide the title compound.

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