반응 #43338

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4-benzyloxy-1-(4-hydroxyphenyl)-1H-pyridin-2-one

2-(diethylamino)ethanol

( 2 )

2-chloro-4-[(4-fluorophenoxy)methyl]pyridine

4-fluorobenzyl bromide

2-methanesulfonyloxymethylpyridine

→

title compound

4-(2-Pyridinylmethoxy)-1-{4-[2-(diethylamino)ethoxy]phenyl}-1H-pyridin-2-one

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실험 절차

Steps (1) and (2) of Example 28 were repeated except that 4-fluorobenzyl bromide used in Example 28 was replaced with 2-methanesulfonyloxymethylpyridine, and successively Example 12 was repeated except that so obtained compound was used in place of 4-benzyloxy-1-(4-hydroxyphenyl)-1H-pyridin-2-one in Step (3) and 2-(1-pyrrolidine)ethanol was replaced with 2-(diethylamino)ethanol, to provide the title compound.

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