반응 #4333

ord-b1ae56670021489c8b0a911be0cc61d1

반응 방정식

Nc1cc(Cl)c(Cl)cc1[N+](=O)[O-]
4,5-dichloro-2-nitroaniline
NCCO
ethanolamine
Nc1cc(NCCO)c(Cl)cc1[N+](=O)[O-]
2-amino-4-β-hydroxyethylamino-5-chloronitrobenzene

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    온도The reaction mixture is heated for 6 hours
  2. 2
    기타After dilution with water and neutralization with concentrated hydrochloric acid, the expected product precipitates

실험 절차

0.11 mole (22.8 g) of 4,5-dichloro-2-nitroaniline is added to a solution of 0.55 mole (33.3 ml) of ethanolamine in 70 ml of dioxane. The reaction mixture is heated for 6 hours in refluxing dioxane. After dilution with water and neutralization with concentrated hydrochloric acid, the expected product precipitates.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US04725283uspto-grants-1988_02