반응 #4328

반응 방정식

acetic acid

sodium nitrite

2,5-dibromo-N-benzenesulphonylaniline

nitric acid

→

2,5-dibromo-4-nitro-N-benzenesulphonylaniline

용매

water

반응 조건

후처리

1. 1
   workup.ADDITIONare added
2. 2
   온도The reaction mixture, cooled beforehand
3. 3
   기타the expected product precipitates
4. 4
   여과It is filtered off
5. 5
   세척washed to neutrality
6. 6
   기타recrystallized from acetic acid

실험 절차

To 250 ml of acetic acid, diluted with 130 ml of water, are added: 1.5 g of sodium nitrite, 0.13 mole of 2,5-dibromo-N-benzenesulphonylaniline prepared in the previous stage and 0.78 mole (32.5 ml) of nitric acid (d=1.52). The reaction mixture is heated for 1 hour at 90° C. The reaction mixture, cooled beforehand, is poured onto 1 kg of ice and the expected product precipitates. It is filtered off, washed to neutrality and then recrystallized from acetic acid; it melts at 148° C.

출처