반응 #43234

반응 방정식

Intermediate 1

3-(2-Chloro-pyrimidin-4-yl)-benzaldehyde

2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

→

5-[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

반응 조건

실험 절차

Intermediate 1 was coupled with 2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester following procedure B. LC-MS showed the product had the expected M+H+ of 401.

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