반응 #43215

반응 방정식

Intermediate 1

3-(2-Chloro-pyrimidin-4-yl)-benzaldehyde

4(R)-amino-3(S)-methyl-piperidine-1-carboxylic acid benzyl ester

→

4(R)-[3-(2-Chloro-pyrimidin-4-yl)-benzylamino]-3(S)-methyl-piperidine-1-carboxylic acid benzyl ester

반응 조건

실험 절차

Intermediate 1 was coupled with 4(R)-amino-3(S)-methyl-piperidine-1-carboxylic acid benzyl ester (prepared according to literature procedure (ref 1)) following procedure B. LC-MS showed the product had the expected M+H+ of 451.

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