반응 #430453

ord-96999947ea9f42a5b2db6509eb790154

반응 방정식

N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O
Trp
NCC(=O)O
( 4 )
NCC(=O)O
Gly
N[C@@H](CCC(=O)O)C(=O)O
Glu
CC(C)[C@H](N)C(=O)O
( 7 )
CC(C)[C@H](N)C(=O)O
Val
C[C@H](N)C(=O)O
Ala
NCCCC[C@H](N)C(=O)O
Lys
N[C@@H](CC(=O)O)C(=O)O
Asp
C[C@@H](O)[C@H](N)C(=O)O
Cys
C[C@@H](O)[C@H](N)C(=O)O
Thr
N=C(N)NCCC[C@H](N)C(=O)O
Arg
CC(C)C[C@H](N)C(=O)O
Leu
CSCC[C@H](N)C(=O)O
Met
CC(C)[C@H](N)C(=O)O
Val
CC[C@H](C)[C@H](N)C(=O)O
Ile
C[C@@H](O)[C@H](N)C(=O)O
Thr
N[C@@H](Cc1ccccc1)C(=O)O
Phe
NCC(=O)O
Gly
→
N[C@@H](CS)C(=O)O
Cys
O=COO
performic acid

반응물

N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O
Trp
NCC(=O)O
( 4 )
NCC(=O)O
Gly
N[C@@H](CCC(=O)O)C(=O)O
Glu
CC(C)[C@H](N)C(=O)O
( 7 )
CC(C)[C@H](N)C(=O)O
Val
C[C@H](N)C(=O)O
Ala
NCCCC[C@H](N)C(=O)O
Lys
N[C@@H](CC(=O)O)C(=O)O
Asp
C[C@@H](O)[C@H](N)C(=O)O
Cys
C[C@@H](O)[C@H](N)C(=O)O
Thr
N=C(N)NCCC[C@H](N)C(=O)O
Arg
CC(C)C[C@H](N)C(=O)O
Leu
CSCC[C@H](N)C(=O)O
Met
CC(C)[C@H](N)C(=O)O
Val
CC[C@H](C)[C@H](N)C(=O)O
Ile
C[C@@H](O)[C@H](N)C(=O)O
Thr
N[C@@H](Cc1ccccc1)C(=O)O
Phe
—
( 3 )
NCC(=O)O
Gly

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Asp (10), 10.33; Thr (1), 0.91; Ser (7), 6.10; Glu (11), 11.82; Pro (3), 3.00; Gly (4), 4.44; Ala (7), 6.91; Cys (1), 1.11; Val (7), 6.60; Met (2), 2.11; Ile (1.01; Leu (10), 10.83, Phe (1), 1.10; Lys (9), 9.32; His (4), 3.75; Arg (5), 5.2 Trp (1), 0.93 (recovery 84.2%; the value for Cys was obtained from the hydrolyzate after oxidation with performic acid.)

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US05861284uspto-grants-1999_01