반응 #429533

반응 방정식

formic acid

1,1-ethylenedioxy-4-(4-n-propylphenyl)cyclohexane

→

4-n-propylphenylcyclohexanone

용매

water

반응 조건

후처리

1. 1
   온도a reflux for 2 hours
2. 2
   온도After cooled
3. 3
   추출extracted with 500 ml of ethyl acetate
4. 4
   세척Organic layer was washed with water
5. 5
   건조dried over anhydrous magnesium sulfate
6. 6
   workup.DISTILLATIONthe solvent was distilled off under a reduced pressure

실험 절차

To 300 ml of formic acid (99%) was put 84 g of the 1,1-ethylenedioxy-4-(4-n-propylphenyl)cyclohexane mentioned above, and stirred under a reflux for 2 hours. After cooled, the reaction solution was added to 500 ml of water and extracted with 500 ml of ethyl acetate. Organic layer was washed with water and dried over anhydrous magnesium sulfate, and the solvent was distilled off under a reduced pressure to obtain 65.6 g of 4-n-propylphenylcyclohexanone.

출처