반응 #427866

반응 방정식

(6-amino-7-methoxy-2,3-dihydro-1H-inden-1-ylidene)acetonitrile

ammonia ethanol

→

title compound

수율 99.0%

3-(2-Aminoethylidene)-4-methoxyindan-5-amine

수율 99.0%

용매

ethanol

반응 조건

후처리

1. 1
   여과The catalyst was filtered off
2. 2
   농축the filtrate was concentrated under reduced pressure

실험 절차

To a solution of (6-amino-7-methoxy-2,3-dihydro-1H-inden-1-ylidene)acetonitrile (15.2 mg, 0.076 mmol) in ethanol (0.5 mL) were added Raney cobalt (150 mg) and 2N ammonia/ethanol solution (0.5 mL), and the mixture was stirred at room temperature for 2 hr under a hydrogen atmosphere. The catalyst was filtered off using celite, and the filtrate was concentrated under reduced pressure to give the title compound (15.3 mg, yield 99%).

출처