반응 #42774
ord-d432949c0c7046e1843b5cf1467f7cf1
반응 방정식
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1세척washed with water (3×100 ml) and saturated brine (50 ml)
- 2건조dried (MgSO4)
- 3여과filtered
- 4기타the filtrate is evaporated
- 5기타to give a pale pink solid
실험 절차
3-(4-Chlorophenyl)-7-hydroxy-2-isopropyl-chromen-4-one (2.3 g, 7.31 mmol) is suspended in dry dichloromethane (140 ml) at room temperature. N-iodosuccinimide (1.73 g, 7.67 mmol) is added, and the mixture is stirred vigorously at room temperature for 30 min. The mixture is diluted with dichloromethane (60 ml), washed with water (3×100 ml) and saturated brine (50 ml), dried (MgSO4) and filtered, and the filtrate is evaporated to give a pale pink solid.