반응 #42744
ord-f6ceb956a24d4e769e39b92cd6f2fd8c
반응 방정식
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1여과The reaction mixture is filtered through a pad of Celite
- 2여과filter aid, which
- 3세척washed with tetrahydrofuran
- 4기타The solvent is removed under reduced pressure
실험 절차
A suspension of 7-benzyloxy-3-(4-chlorophenyl)-2-isopropyl-8-methoxy-chromen-4-one (2.68 g, 6.16 mmol) and Pd/carbon (20%, 268 mg) in tetrahydrofuran (30 ml), absolute ethanol (30 ml) and 5M HCl solution (15 ml) is stirred under a balloon of H2 at room temperature for 3 h. The reaction mixture is filtered through a pad of Celite filter aid, which is itself washed with tetrahydrofuran. The solvent is removed under reduced pressure to afford the desired product, which is used without further purification.