반응 #42519

반응 방정식

methyl quinoline-7-carboxylate

→

methyl 1,2,3,4-tetrahydroquinoline-7-carboxylate

수율 98.8%

용매

methanol

반응 조건

후처리

1. 1
   여과The reaction mixture was filtered through diatomaceous earth
2. 2
   농축concentrated under reduced pressure

실험 절차

A solution of methyl quinoline-7-carboxylate (185 mg, 1.0 mmol) and PtO2 (20 mg) in methanol (10 mL) was shaken under an atmosphere of hydrogen for 2 h. The reaction mixture was filtered through diatomaceous earth, and concentrated under reduced pressure to provide methyl 1,2,3,4-tetrahydroquinoline-7-carboxylate (189 mg): ESI MS m/z 192 [M+H]+.

출처