반응 #425140

ord-42716c07dab34899b932347ccd36a013

반응 방정식

Cn1nccc1[C@H]1CCCC[C@@H]1O
(1S*,2R*)-2-(1-methyl-1H-pyrazol-5-yl)cyclohexanol
→
Cn1nccc1[C@@H]1CCCC[C@H]1O
title compound
Cn1nccc1[C@@H]1CCCC[C@H]1O
(1R,2S)-2-(1-Methyl-1H-pyrazol-5-yl)cyclohexanol

반응물

Cn1nccc1[C@H]1CCCC[C@@H]1O
(1S*,2R*)-2-(1-methyl-1H-pyrazol-5-yl)cyclohexanol

시약

없음

용매

CCCCCC.CCO
hexane ethanol

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

The (1S*,2R*)-2-(1-methyl-1H-pyrazol-5-yl)cyclohexanol prepared in Example 4a was optically resolved with CHIRALPAK IB (Daicel Corp.; hexane/ethanol=9:1) to yield the title compound as a colorless oil.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US08889741B2uspto-grants-2014_11