반응 #425047

반응 방정식

1-methyl-1H-1,2,3-triazole

n-butyl lithium

cyclohexene oxide

→

title compound

수율 4.5%

(1S*,2R*)-2-(1-Methyl-1H-1,2,3-triazol-5-yl)cyclohexanol

수율 4.5%

용매

THF

반응 조건

후처리

1. 1
   기타The reaction and aftertreatment

실험 절차

The reaction and aftertreatment were conducted in the same manner as in Example 8a by using 1-methyl-1H-1,2,3-triazole (2.00 g, 24.1 mmol), n-butyl lithium (2.69 M solution in hexane; 9.0 mL, 24.2 mmol), cyclohexene oxide (2.40 g, 24.5 mmol) and THF (70 mL), to yield the title compound (197 mg, 4.5%) as a colorless oil.

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