반응 #422231
ord-da2eefd0dd944cde9cff264726e045a2
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1여과the reaction was filtered
- 2세척the filter cake was washed with acetic acid (40 mL) and hexanes (150 mL)
실험 절차
To a solution of 1-hydroxy-2-naphthoic acid (10.2 g, 53.9 mmol) in 100 mL of acetic acid was added bromine (6.60 mL, 53.9 mmol) dropwise. After 72 hours, the reaction was filtered and the filter cake was washed with acetic acid (40 mL) and hexanes (150 mL) to provide 4-bromo-1-hydroxy-2-naphthoic acid that gave a proton NMR spectra consistent with theory.