반응 #421803

반응 방정식

HCl

2-(4-(pyridin-2-yl)but-3-ynyl)-2H-benzo[d][1,2,3]triazole

→

2-(4-(pyridin-2-yl)but-3-ynyl)-2H-benzo[d][1,2,3]triazole hydrochloride

수율 60.0%

용매

dioxane

반응 조건

후처리

1. 1
   온도The reaction mixture was cooled in the fridge for 1 hour
2. 2
   여과The resulting precipitate was filtered
3. 3
   세척washed with cold dioxane and diethyl ether
4. 4
   기타dried

실험 절차

A solution of HCl (0.8 N, 906 μl) was added to a solution of 2-(4-(pyridin-2-yl)but-3-ynyl)-2H-benzo[d][1,2,3]triazole (90 mg) in dioxane (5 mL). The reaction mixture was cooled in the fridge for 1 hour. The resulting precipitate was filtered, washed with cold dioxane and diethyl ether and dried to yield 2-(4-(pyridin-2-yl)but-3-ynyl)-2H-benzo[d][1,2,3]triazole hydrochloride (99 mg, 0.35 mmol, 60%) as a white solid.

출처