반응 #42077

반응 방정식

4-chlorobenzyl 2,4-dichlorophenyl ketone

dimethyl-formamide dimethylacetal

→

crude product

3-Dimethylamino-1-(2,4-dichlorophenyl)-2-(4-chlorophenyl)prop-2-en-1-one

용매

DMF

반응 조건

후처리

1. 1
   기타The volatiles were removed in vacuo

실험 절차

A solution of 4-chlorobenzyl 2,4-dichlorophenyl ketone (4.5 g, 14.4 mmol) and dimethyl-formamide dimethylacetal (7.7 mL, 58 mmol) in DMF (60 mL) was heated at 75° C. for 20 h. The volatiles were removed in vacuo to provide the crude product which was used directly in the next step. HPLC/MS: 354 (M+1), 356 (M+3); Rt=3.47 min.

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