반응 #41808

반응 방정식

hexane EtOAc

3-phenoxyaniline

thiophosgene

→

3-phenoxyphenylisothiocyanate

용매

acetone

반응 조건

후처리

1. 1
   기타the resulting reaction
2. 2
   온도maintained for 30 min
3. 3
   농축The reaction was concentrated
4. 4
   기타azeotroped with toluene
5. 5
   기타taken on without further purification

실험 절차

To a stirring solution of 3-phenoxyaniline (185 mg, 1.0 mmol) in acetone (4.0 mL) at 0° C. was added thiophosgene (0.23 mL, 3.0 mmol) and the resulting reaction maintained for 30 min. The reaction determined complete by TLC (4:1 hexane/EtOAc). The reaction was concentrated, azeotroped with toluene and taken on without further purification.

출처