반응 #417923

반응 방정식

28

methyl 2-hydroxybenzoate

K2CO3

13

1-iodoundec-4Z-ene

→

yellow oil

수율 90.0%

methyl 2-(undec-4Z-enyloxy)benzoate

수율 90.0%

용매

DMF

반응 조건

후처리

1. 1
   기타After reaction for 8 hours at 90° C.
2. 2
   농축the reaction medium is concentrated
3. 3
   세척washed with water

실험 절차

88 mg of 28 (578 μmol) and 77 mg of K2CO3 (557 mmol) are added to 140 mg of 13 (500 μmol) in anhydrous DMF (2 mL). After reaction for 8 hours at 90° C., the reaction medium is concentrated, taken up in DCM and then washed with water. 137 mg of a yellow oil are obtained, and are chromatographed on silica gel in pentane/ethyl acetate (40/1). 100 mg of a yellow oil are isolated, i.e. a yield of 66%.

출처