반응 #417919

반응 방정식

PCC

alcohol

3-(undec-4Z-enyloxy)benzyl alcohol

→

yellow oil

수율 99.1%

3-(undec-4Z-enyloxy)benzaldehyde

수율 99.1%

용매

DCM

반응 조건

후처리

1. 1
   건조dried by coevaporation with toluene
2. 2
   온도The reaction is heated to the reflux point of the DCM for 1 hour
3. 3
   온도After cooling
4. 4
   workup.ADDITIONthe reaction medium is diluted with ether
5. 5
   여과filtered through Florisil
6. 6
   농축After concentrating

실험 절차

10 mL of anhydrous DCM and then 190 mg of PCC (881 μmol) are added under argon to 120 mg of alcohol 16 (434 μmol) dried by coevaporation with toluene. The reaction is heated to the reflux point of the DCM for 1 hour. After cooling, the reaction medium is diluted with ether and filtered through Florisil. After concentrating, 118 mg of a yellow oil are obtained, i.e. a yield of 99%.

출처