반응 #41780

ord-4b4b851f6c574ce7b9e369a2ecc32f20

반응 방정식

COC(=O)c1cncc(Oc2ccc([N+](=O)[O-])cc2)c1
methyl-5-(4-nitrophenoxy)pyridine-3-carboxylate
→
COC(=O)c1cncc(Oc2ccc(N)cc2)c1
methyl5-[4-aminophenoxy]pyridine-3-carboxylate

반응물

COC(=O)c1cncc(Oc2ccc([N+](=O)[O-])cc2)c1
methyl-5-(4-nitrophenoxy)pyridine-3-carboxylate

시약

[Pd]
Pd/C

용매

CO
methanol

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

The mixture containing methyl-5-(4-nitrophenoxy)pyridine-3-carboxylate in methanol with catalytic amount of 10% Pd/C was hydrogenated to yield methyl5-[4-aminophenoxy]pyridine-3-carboxylate. MS: MH+=244.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07728010B2uspto-grants-2010_06