반응 #41571

반응 방정식

hydrogen

5-(2-cyano-phenoxy)-4-(6-methanesulfonyl-pyridin-3-yloxy)-2-nitro-phenylamine

→

4-(2-cyano-phenoxy)-5-(6-methanesulfonyl-pyridin-3-yloxy)-benzene-1,2-diamine

용매

methanol

반응 조건

후처리

1. 1
   기타obtained in (step 4)
2. 2
   기타the reaction liquid
3. 3
   기타The catalyst was removed through filtration
4. 4
   기타the solvent was evaporated away under reduced pressure
5. 5
   기타to obtain the entitled compound

실험 절차

20 mg of developed Raney nickel catalyst was added to a methanol (5 ml) solution of 161 mg of 5-(2-cyano-phenoxy)-4-(6-methanesulfonyl-pyridin-3-yloxy)-2-nitro-phenylamine obtained in (step 4), and the reaction liquid was stirred overnight in a hydrogen atmosphere. The catalyst was removed through filtration, and the solvent was evaporated away under reduced pressure to obtain the entitled compound.

출처