반응 #412622

반응 방정식

anhydride

7-oxabicyclo [2.2.1]hept-2-ene-5,6-dicarboxylic acid anhydride

2-hydroxyethyl acrylate

→

desired compound

2-(Acryloyloxy)ethyl 5-carboxy-7-oxabicyclo [2.2.1]hept-2-ene-6-carboxylate

용매

toluene

반응 조건

후처리

1. 1
   workup.DISTILLATIONthe toluene was distilled off under reduced pressure

실험 절차

Maleic anhydride (50 g) and furan (150 ml) were heated under reflux for 1 hour, and then the excess of furan was distilled off. The residue was recrystallised from chloroform, yielding 72 g of 7-oxabicyclo [2.2.1]hept-2-ene-5,6-dicarboxylic acid anhydride (m.pt. 110° C., decomp.). This anhydride (40 g) and 30.75 g of 2-hydroxyethyl acrylate were heated in 250 ml of toluene at 100° C. for 3 hours, and then the toluene was distilled off under reduced pressure, leaving the desired compound as a viscous liquid.

출처