반응 #410060

반응 방정식

3-benzyloxyphenol

3-(3-thienylmethoxy)phenol

ethyl (RS)-4-[3-(3-thienylmethoxy)phenoxy]-4-phenylbutanoate

2-hydroxy-4-benzyloxy-N-ethylbenzamide

ethyl (RS)-4-chloro-4-phenylbutanoate

4-phenylbutanoate

→

ethyl (RS)-4-[2-(N-ethylcarbamoyl)-5-benzyloxyphenoxy]-4-phenyl-butanoate

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실험 절차

By proceeding in a similar manner, but replacing methyl 4-benzyloxy-2-hydroxybenzoate with 3-benzyloxyphenol and ethyl (RS)-4-chloro-4-phenylbutanoate with ethyl (RS)-4-chloro-4-(2-methyl)phenylbutanoate, there is prepared ethyl (RS)-4-[(3-benzyloxy)phenoxy]-4-(2-methylphenyl)butanoate. By proceeding in a similar manner, but replacing methyl 4-benzyloxy-2-hydroxybenzoate with 3-(3-thienylmethoxy)phenol, there is prepared ethyl (RS)-4-[3-(3-thienylmethoxy)phenoxy]-4-phenylbutanoate. By proceeding in a similar manner, but replacing methyl 4-benzyloxy-2-hydroxybenzoate with 2-hydroxy-4-(3-thienylmethoxy)acetophenone, there is prepared ethyl (RS)-4-[2-acetyl-5-(3-thienylmethoxy)phenoxy)]-4-phenylbutanoate. By proceeding in a similar manner but replacing methyl 4-benzyloxy-2-hydroxybenzoate with 2-hydroxy-4-benzyloxy-N-ethylbenzamide there is obtained ethyl (RS)-4-[2-(N-ethylcarbamoyl)-5-benzyloxyphenoxy]-4-phenyl-butanoate. By proceeding in a similar manner but replacing methyl 4-benzyloxy-2-hydroxybenzoate with 2-hydroxy-4-(3-thienylmethoxy)acetophenone and ethyl (RS)-4-chloro-4-phenylbutanoate with ethyl (RS)-4-chloro-4-(2-methylphenyl)butanoate, there is prepared ethyl (RS)-4-[2-acetyl-5-(3-thienylmethoxy)phenoxy]-4-(2-methylphenyl)-butanoate. By proceeding in a similar manner, but replacing methyl 4-benzyloxy-2-hydroxybenzoate with 2-hydroxy-4-(3-pyridylmethoxy)acetophenone, there is prepared ethyl (RS)-4-[2-acetyl-5-(3-pyridylmethoxy)phenoxy]-4-phenylbutanoate. By proceeding in a similar manner, but replacing methyl 4-benzyloxy-2-hydroxybenzoate with 4-benzyloxy-2-hydroxybenzamide, there is prepared ethyl (RS)-4-[2-carbamoyl-5-benzyloxyphenoxy]-4-phenylbutanoate. By proceeding in a similar manner, but replacing methyl 4-benzyloxy-2-hydroxybenzoate with 4-benzyloxy-2-hydroxy-N,N-dimethylbenzamide, there is prepared ethyl (RS)-4-[2-N,N-dimethylcarbamoyl-5-benzyloxyphenoxy]-4-phenylbutanoate. By proceeding in a similar manner. but replacing methyl 4-benzyloxy-2-hydroxybenzoate with 4-(3-thienylmethoxy)-2-hydroxybenzamide and ethyl (RS)-4-chloro-4-phenylbutanoate with ethyl (RS)-4-chloro-4-(2-methylphenyl)butanoate, there is prepared ethyl (RS)-4-[2-carbamoyl-5-(3-thienylmethoxy)phenoxy]-4-(2-methylphenyl)butanoate.

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