반응 #409914

반응 방정식

L-phenylalanine methyl ester hydrochloride

cyclohex-1-enylacetic acid

N-(L-alaninyl)-L-phenylalanine methyl ester

N-BOC-L-alanine

→

N-[N-(Cyclohex-1-enylacety)-L-alaninyl]-L-phenylalanine Methyl Ester

반응 조건

후처리

1. 1
   기타prepared
2. 2
   기타followed by removal of the BOC-group
3. 3
   기타was prepared as a solid (mp=139-142° C.)

실험 절차

Following General Procedure U and using cyclohex-1-enylacetic acid (Alfa) and N-(L-alaninyl)-L-phenylalanine methyl ester (prepared by coupling N-BOC-L-alanine (Bachem) with L-phenylalanine methyl ester hydrochloride (Bachem) using General Procedure U, followed by removal of the BOC-group using General Procedure Y), the title compound was prepared as a solid (mp=139-142° C.). The reaction was monitored by tlc (Rf=0.27 in 1:1 EtOAc/hexanes).

출처