반응 #409591

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1-[3-(3-hydroxyphenyl)propyl]imidazole

4-chloromethyl-2-phenyloxazole

→

4-[3-[3-(1-imidazolyl)propyl]phenoxymethyl]-2-phenyloxazole

수율 78.0%

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실험 절차

In substantially the same manner as in Working Example 72, 1-[3-(3-hydroxyphenyl)propyl]imidazole was allowed to react with 4-chloromethyl-2-phenyloxazole to give 4-[3-[3-(1-imidazolyl)propyl]phenoxymethyl]-2-phenyloxazole. The yield was 78%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 62-63° C.

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