반응 #409580

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1-[3-(4-hydroxyphenyl)propyl]imidazole

4-chloromethyl-2-(9-fluorenone-2-yl)oxazole

→

2-(9-fluorenone-2-yl)-4-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]oxazole

수율 86.0%

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실험 절차

In substantially the same manner as in Working Example 72, 1-[3-(4-hydroxyphenyl)propyl]imidazole was allowed to react with 4-chloromethyl-2-(9-fluorenone-2-yl)oxazole to give 2-(9-fluorenone-2-yl)-4-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]oxazole. The yield was 86%. Recrystallization from ethanol gave yellow needles, mp 153-154° C.

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