반응 #409558

반응 방정식

1-[3-(4-hydroxyphenyl)propyl]imidazole

2-benzyl-4-chloromethyloxazole

→

2-benzyl-4-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]oxazole

수율 23.0%

반응 조건

실험 절차

In substantially the same manner as in Working Example 37, 1-[3-(4-hydroxyphenyl)propyl]imidazole was allowed to react with 2-benzyl-4-chloromethyloxazole to give 2-benzyl-4-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]oxazole. The yield was 23%. Recrystallization from ethyl acetate-isopropyl ether gave colorless prisms, mp 61-62° C.

출처