반응 #409556

반응 방정식

1-[3-(4-hydroxyphenyl)propyl]imidazole

4-chloromethyl-2-(3,4-dihydro-2-naphthyl)oxazole

→

2-(3,4-dihydro-2-naphthyl)-4-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]oxazole

수율 42.0%

반응 조건

실험 절차

In substantially the same manner as in Working Example 37, 1-[3-(4-hydroxyphenyl)propyl]imidazole was allowed to react with 4-chloromethyl-2-(3,4-dihydro-2-naphthyl)oxazole to give 2-(3,4-dihydro-2-naphthyl)-4-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]oxazole. The yield was 42%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 99-100° C.

출처