반응 #40826

반응 방정식

NaCNBH3

5-(4-trifluoromethylphenyl)-6-phenyl-pyridine-2-carbaldehyde

Compound 57

5-(4-trifluoromethylphenyl)-6-phenyl-pyridine-2-carbaldehyde

(3-amino-propyl)-phosphonic acid

→

title compound

(3-{[6-Phenyl-5-(4-trifluoromethylphenyl)-pyridin-2-ylmethyl]-amino}-propyl)-phosphonic Acid

용매

MeOH

MeOH

반응 조건

후처리

1. 1
   기타were reacted

실험 절차

Following General Procedure M, 5-(4-trifluoromethylphenyl)-6-phenyl-pyridine-2-carbaldehyde (Compound 57, 58 mg, 0.18 mmol), (3-amino-propyl)-phosphonic acid (25 mg, 0.18 mmol), Bu4NOH (0.18 ml, 0.18 mmol, 1 M in MeOH) and NaCNBH3 (11 mg, 0.18 mmol) in MeOH (3 ml) were reacted to produce the title compound as a white solid.

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