반응 #4074

반응 방정식

(S)-2-(6-methoxy-2-naphthyl)propionic acid

hydrogen chloride

→

isobutyl (S)-2-(6-methoxy-2-naphthyl)propionate

용매

isobutyl alcohol

반응 조건

후처리

1. 1
   workup.DISTILLATIONthe excess alcohol is distilled off in vacuo
2. 2
   기타the residue is purified by chromatography

실험 절차

A solution of 300 mg of (S)-2-(6-methoxy-2-naphthyl)propionic acid in 5 ml of isobutyl alcohol is saturated with hydrogen chloride. After 24 hours, the excess alcohol is distilled off in vacuo and the residue is purified by chromatography using an alumina substrate to yield isobutyl (S)-2-(6-methoxy-2-naphthyl)propionate.

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