반응 #4073

ord-969a0003bb064226bfa65a3513e9c62c

반응 방정식

COc1ccc2cc([C@H](C)C(=O)O)ccc2c1
(S)-2-(6-methoxy-2-naphthyl)-propionic acid
[Na+].[OH-]
sodium hydroxide
COc1ccc2cc([C@H](C)C(=O)[O-])ccc2c1.[Na+]
sodium (S)-2-(6-methoxy-2-naphthyl)propionate

용매

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타The solvent is evaporated in vacuo
  2. 2
    기타followed by precipitation with ether

실험 절차

To a solution of 300 mg of (S)-2-(6-methoxy-2-naphthyl)-propionic acid in 5 ml of methanol is added a 1 molar equivalent of sodium hydroxide, in the form of a 0.1N solution. The solvent is evaporated in vacuo and the residue is taken up in 2 ml of methanol, followed by precipitation with ether, to yield crude sodium (S)-2-(6-methoxy-2-naphthyl)propionate.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US04723033uspto-grants-1988_02