반응 #4071

반응 방정식

methyl α-(2-methylphenyl)-β-methoxyacrylate

N-bromosuccinimide

succinimide

→

colorless crystals

수율 97.3%

Methyl α-(2-bromomethylphenyl)-β-methoxyacrylate

수율 97.3%

용매

CCl4

반응 조건

후처리

1. 1
   여과The mixture is filtered
2. 2
   기타the filtrate is evaporated down
3. 3
   workup.DISSOLUTIONthe oil which remains is dissolved in about 5 ml of acetone
4. 4
   기타brought to crystallization with n-hexane

실험 절차

20.6 g of the methyl α-(2-methylphenyl)-β-methoxyacrylate obtained as described in method A, 17.65 g of N-bromosuccinimide, 0.2 g of azobisisobutyronitrile and 150 ml of CCl4 are slowly heated to 90° C. and kept at this temperature until all of the succinimide floats on the solvent. The mixture is filtered, the filtrate is evaporated down, and the oil which remains is dissolved in about 5 ml of acetone and brought to crystallization with n-hexane. 27.5 g of colorless crystals of melting point 86°-87° C. are obtained.

출처