반응 #4069

반응 방정식

N-bromosuccinimide

methyl phenylacetate

→

title compound

수율 93.1%

Methyl Bromo-Phenylacetate

수율 93.1%

용매

carbon tetrachloride

반응 조건

후처리

1. 1
   온도to reflux
2. 2
   온도refluxed for about 12 hours
3. 3
   여과filtered
4. 4
   농축The filtrate was concentrated by evaporation under vacuum

실험 절차

In this example, a mixture containing 5.93 g of N-bromosuccinimide, 5.0 g of methyl phenylacetate; and a catalytic amount (about 0.1 g) of benzoyl peroxide in 50 ml of carbon tetrachloride was warmed to reflux and then refluxed for about 12 hours. The mixture was then cooled to about 0° C. and filtered. The filtrate was concentrated by evaporation under vacuum affording 7.1 g of the title compound as an oil.

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