반응 #40557

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6-Chloro-3-methoxypyridazine-4-carbaldehyde

2,3-diaminotoluene

→

2-(6-Chloro-3-methoxypyridazin-4-yl)-7-methyl-1H-benzimidazole

용매

DMF

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후처리

1. 1
   기타The crude product is purified on silica gel (eluent ethyl acetate in heptane)

실험 절차

6-Chloro-3-methoxypyridazine-4-carbaldehyde is dissolved in DMF, und 2,3-diaminotoluene is added. The reaction solution is heated at 120° C. in a microwave for 30 minutes. The crude product is purified on silica gel (eluent ethyl acetate in heptane). MS (ES+) m/z 275 (M+H).

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