반응 #40368

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(6-benzyloxy-4H-benzo[1,4]oxazin-3-one)-glyoxal hydrate

1,1-dimethyl-2-(4-hydroxyphenyl)ethylamine

hydrochloride

→

title compound

8-{2-[1,1-dimethyl-2-(4-hydroxyphenyl)ethylamino]-1-hydroxyethyl}-6-benzyloxy-4H-benzo[1,4]oxazin-3-one

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실험 절차

The title compound is prepared from 10 g of (6-benzyloxy-4H-benzo[1,4]oxazin-3-one)-glyoxal hydrate and 4.6 g of 1,1-dimethyl-2-(4-hydroxyphenyl)ethylamine analogously to the method for Example 3(a). Yield: 9.0 g (64%, hydrochloride); melting point: 255° C.-258° C.

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