반응 #40351

ord-c83558528a69411cbdd1d98c6c51341f

반응 방정식

CC1CCc2cc3[nH]c(=O)cc(C(F)(F)F)c3cc2N1CC1CC1
Compound 187
CC1CCc2cc3[nH]c(=O)cc(C(F)(F)F)c3cc2N1CC1CC1
4-Trifluoromethyl-7-methyl-6-cyclopropylmethyl-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-one
CC=O
acetaldehyde
CCN1c2cc3c(C(F)(F)F)cc(=O)[nH]c3cc2CCC1C
4-Trifluoromethyl-7-methyl-6-ethyl-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-one

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타This compound was prepared in a similar fashion as

실험 절차

This compound was prepared in a similar fashion as that described in Example 84 from Compound 187 (Structure 33 of Scheme VI, where R1=methyl, n=1) and acetaldehyde. 1H NMR (400 MHz, CDCl3) 11.19 (br. s, 1H), 7.11 (s, 1H), 7.00 (s, 1H), 6.80 (s, 1H), 3.55 (m, 1H), 3.47-3.32 (m, 2H), 2.93-2.80 (m, 2H), 1.93-1.79 (m, 2H), 1.22 (t, 3H, J=7.0), 1.18 (d, 3H, J=6.4).

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07727980B2uspto-grants-2010_06