반응 #40329

ord-d3ec7ce35c5743429efed8cc6b073b42

반응 방정식

Fc1ccc(C2=CCC3(CC2)OCCO3)cc1
8-(4-fluorophenyl)-1,4-dioxaspiro[4.5]dec-7-ene
[H][H]
hydrogen
Fc1ccc(C2CCC3(CC2)OCCO3)cc1
8-(4-fluorophenyl)-1,4-dioxaspiro[4.5]decane

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

8-(4-fluorophenyl)-1,4-dioxaspiro[4.5]dec-7-ene is hydrogenated using Pd/C with hydrogen. After filtering-off of the catalyst over celite and evaporating-off of the solvent, 8-(4-fluorophenyl)-1,4-dioxaspiro[4.5]decane is obtained in a quantitative yield: tR 3.65 min (LC-1); ESI-MS(+): m/z 237.26 [M+H]+.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07727979B2uspto-grants-2010_06