반응 #40293

반응 방정식

2-chloroethylamine hydrochloride

K2CO3

4-t-butylbenzenethiol

→

clear oil

수율 74.1%

2-(4-t-butylphenylthio)ethylamine

수율 74.1%

용매

CHCl3

반응 조건

후처리

1. 1
   세척The mixture was washed three times with distilled water
2. 2
   건조dried with MgSO4
3. 3
   여과filtered
4. 4
   기타Volatiles were removed in vacuo

실험 절차

To a stirring mixture of 4.36 g (38.0 mmol) of 2-chloroethylamine hydrochloride and 12.00 g (87.0 mmol) of K2CO3 in 30 mL of CHCl3 was added 4.82 g (29.0 mmol) of 4-t-butylbenzenethiol. The mixture was stirred at 50° C. in a sealed vial overnight. The mixture was washed three times with distilled water, dried with MgSO4 and filtered. Volatiles were removed in vacuo leaving 4.50 g (74%) of clear oil. 1H NMR (300 MHz, CDCl3): δ=7.32, m, 4H; 2.93, m, 4H; 1.42, broad singlet, 2H; 1.30, s, 9H.

출처