반응 #3871
ord-f0acfd39ea7a462683b5b3c43269d05e
반응 방정식
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1세척washed with 5% aq. HCl
- 2세척The acidic solution is washed with ether
- 3기타basified, affording an oil which
- 4세척washed with sat'd NaCl
- 5기타dried
- 6여과filtered
- 7기타evaporated in vacuo
실험 절차
Potassium hydroxide (1.47 g), tetrabutyl ammonium chloride (0.77 g) and H2O (1 ml) are added to a solution of the product obtained in Step 6. (6.6 g) in 1,3-dibromopropane (27 ml). The reaction mixture is stirred for 20 hours and diluted with diethyl ether and washed with 5% aq. HCl. The acidic solution is washed with ether and basified, affording an oil which is taken up in ether, washed with sat'd NaCl, dried, filtered and evaporated in vacuo affording the desired product as an oil.