반응 #3867

ord-11041e93a6764496b437ae0e8552152e

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    추출extracted with 5% aq. HCl
  2. 2
    세척The acidic solution is washed with ether
  3. 3
    기타dried
  4. 4
    여과filtered
  5. 5
    기타evaporated in vacuo

실험 절차

Crushed potassium hydroxide (4.1 g) and tetrabutyl ammonium chloride (2.2 g) and H2O (5 ml) are added to a stirred mixture of the product obtained in Step 3. (17.2 g) and 1,3-dibromopropane (74.8 ml). The reaction mixture is stirred under nitrogen overnight, diluted with diethyl ether, and extracted with 5% aq. HCl. The acidic solution is washed with ether, sat'd NaCl, dried, filtered and evaporated in vacuo yielding the desired product as an oil.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US04722925uspto-grants-1988_02