반응 #3846

반응 방정식

Allyl bromide

N-(2-trifluoromethylphenyl)-2-pyridinesulfonamide 1-oxide

NaH

→

title compound

N-allyl-N-(2-trifluoromethylphenyl)-2-pyridinesulfonamide 1-oxide

용매

DMF

반응 조건

후처리

1. 1
   workup.STIRRINGthe mixture is stirred at RT for 48 hours
2. 2
   기타purified

실험 절차

To N-(2-trifluoromethylphenyl)-2-pyridinesulfonamide 1-oxide (compound 129, Table A) (1.0 g, 3.0 mmol) in 10 ml of DMF is added NaH (0.30 g, 6.2 mmol) under N2, and the mixture is stirred at RT for 30 minutes. Allyl bromide (0.82 g, 0.59 ml, 6.8 mmol) is added dropwise, and the mixture is stirred at RT for 48 hours. It is then worked up and purified to give the title compound (compound 37, Table A). (DMF is dimethylformamide; RT is room temperature.)

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