반응 #3842

ord-950cfed0e8884a9ab3f2f0fdcbee3869

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    온도refluxed for 16 hours
  2. 2
    온도The solution was cooled
  3. 3
    농축concentrated in vacuo
  4. 4
    기타leaving a yellow liquid
  5. 5
    기타The crude product was purified

실험 절차

To a solution of 2-mercaptobenzophenone (2.3 g, 7.4 mmol) in diethyl ether (10 mL) was added dropwise diethyl azodicarboxylate (0.65 g, 3.7 mmol). The solution was stirred for 5 minutes at room temperature, then diluted with benzene (40 mL) and refluxed for 16 hours. The solution was cooled and concentrated in vacuo leaving a yellow liquid. The crude product was purified using silica gel chromatography (75% hexane/25% ethyl acetate) to give the title compound as a yellow foam (0.8 g, 50%);

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US05734081uspto-grants-1998_03