반응 #3806

반응 방정식

2,2'-dithiobisbenzoyl chloride

4-tert-butylaniline

→

title compound

수율 12.1%

2,2'-Dithiobis[N-[4-(1,1-dimethylethyl)phenyl]benzamide]

수율 12.1%

용매

dichloromethane

pyridine

반응 조건

후처리

1. 1
   농축The mixture was concentrated
2. 2
   기타the residue triturated with 5% aqueous HCl
3. 3
   여과the resulting solid was collected by filtration
4. 4
   세척washed with water
5. 5
   기타to yield the crude product
6. 6
   기타The crude material was recrystallized from ethyl ether-ethanol

실험 절차

A solution of 2,2'-dithiobisbenzoyl chloride (1.20 g, 3.50 mmol) in 25 mL of dichloromethane was added to a solution of 4-tert-butylaniline (1.04 g, 6.99 mmol) in 8 mL of pyridine at 23° C. The reaction mixture was stirred for 18 hours at 23° C. under nitrogen atmosphere. The mixture was concentrated, the residue triturated with 5% aqueous HCl, and the resulting solid was collected by filtration and washed with water to yield the crude product. The crude material was recrystallized from ethyl ether-ethanol to yield 0.24 g of the title compound, mp 135°-138° C.

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