반응 #3784

반응 방정식

1,2-bis(2-methyl-5-trimethylsilyl-3-thienyl)hexafluorocyclopentene

hydrobromic acid

→

1,2-bis(2-methyl-3-thienyl)hexafluorocyclopentene

수율 98.0%

용매

chloroform

반응 조건

후처리

1. 1
   기타to react for 6 hours under refluxing conditions
2. 2
   기타After the completion of the reaction
3. 3
   세척the chloroform layer was washed with an aqueous solution of sodium bicarbonate
4. 4
   기타the chloroform was removed under reduced pressures
5. 5
   기타The reaction product was purified by silicagel column chromatogram

실험 절차

1,2-bis(2-methyl-5-trimethylsilyl-3-thienyl)hexafluorocyclopentene (2.16 g, 0.005 mol) was dissolved in chloroform (200 ml) and was allowed to react for 6 hours under refluxing conditions by adding concentrated hydrobromic acid (10 ml) to the solution. After the completion of the reaction, the chloroform layer was washed with an aqueous solution of sodium bicarbonate and the chloroform was removed under reduced pressures. The reaction product was purified by silicagel column chromatogram to give 1,2-bis(2-methyl-3-thienyl)hexafluorocyclopentene (1.8 g, 0.0049 mol).

출처