반응 #367982

반응 방정식

2-amino-4,6-dimethylpyrimidine

2-methoxycarbonylbenzenesulfonylisocyanate

→

N-[(4,6-Dimethylpyrimidin-2-yl)aminocarbonyl]-2-methoxycarbonylbenzenesulfonamide

용매

acetonitrile

반응 조건

후처리

1. 1
   workup.STIRRINGThe resulting mixture was thereafter stirred for sixteen hours
2. 2
   여과filtered
3. 3
   기타to remove the desired product which
4. 4
   기타had precipitated as a white solid, m.p. 198°-202°
5. 5
   기타absorption peaks at 1750, 1700, 1600 and 1550 cm-1

실험 절차

To 37 g. of 2-amino-4,6-dimethylpyrimidine in 500 ml of anhydrous acetonitrile was added 67 g of 2-methoxycarbonylbenzenesulfonylisocyanate with stirring at ambient temperatures. The resulting mixture was thereafter stirred for sixteen hours and then filtered to remove the desired product which had precipitated as a white solid, m.p. 198°-202°. It showed infrared absorption peaks at 1750, 1700, 1600 and 1550 cm-1, consistent for the desired compound.

출처