반응 #367690

ord-bc6187862d6e41b7a7c4d2fedb6c0ebe

반응 방정식

NC(=O)CC[C@H](N)C(=O)O
glutamine
NC(=O)CC[C@H](N)C(=O)O
(S)-glutamine
CO
methanol
O
water
CC#N
acetonitrile
NC(=O)CC[C@@H](N)C(=O)O
(R)-glutamine

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Example 1 was repeated with the difference that the sample to be tested was a glutamine of unknown enantiomer composition, the comparison samples were (RS)-, (R)-, and (S)-glutamine, and the mobile phase was a mixture of methanol, water, acetonitrile, and tetrahydrofuran in a 1:1:2:2 ratio by volume. In this case, the (R)-glutamine gave a spot with an Rf -value of 0.70 and the (S)-glutamine gave a spot with an Rf -value of 0.62.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US04590167uspto-grants-1986_05